Infections with Mycoplasma genitalium and Mycoplasma hominis are often asymptomatic. They are caused by tiny bacteria without cell walls, which determines their natural resistance to such antibiotics as penicillin, cephalosporin and vancomycin.
Infections caused by Mycoplasma hominis bacteria are common in sexually active people (up to 50% of them). Infection leads primarily to vaginosis, i.e. vaginal inflammation caused by the bacteria, and in the case of pregnant women, it may contribute to premature childbirth. Chronic infection can be the cause of pyelonephritis, puerperal fever or systemic infection in immunosuppressed patients.
Mycoplasma genitalium infections are less common, but are a common cause of non-gonococcal urethritis. They also lead to the Pelvic Inflammatory Disease (PID). Complications include urethritis in both sexes and cervicitis in women. There is a link between Mycoplasma genitalium infection and endometritis and fertility problems in women. It has been observed that Mycoplasma genitalium infection increases the susceptibility to HIV infection.
The treatment of mycoplasmosis is dependent on the infectious agent. Erythromycin or tetracyclines are usually used. Mycoplasma hominis is resistant to erythromycin, and therefore clindamycin is the drug of choice.
In the case of a positive test result for an infection of the intimate areas, the partner and the persons with whom you have had sexual intercourse during the last two months should be informed immediately. Partners should also be tested for the infection. Sexual restraint should be maintained during and up to one week after the end of treatment.